Conservation of function between mammalian and plant steroid 5 -reductases
نویسندگان
چکیده
منابع مشابه
Conservation of function between mammalian and plant steroid 5alpha-reductases.
Arabidopsis det2 mutants are small dark-green dwarfs displaying pleiotropic defects in light-regulated development during multiple stages of the plant life cycle. The DET2 gene encodes a protein that shares approximately 40% sequence identity with mammalian steroid 5alpha-reductases and is implicated in the synthesis of a class of plant steroids, the brassinosteroids. Here we show that the DET2...
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Dihydrofolate reductase (EC 1.5.1.3) catalyses the NADPHdependent reduction of dihydrofolate to tetrahydrofolate. The product, together with other reduced folates, serves as a cofactor in a variety of 1-carbon transfers in the biosynthesis of purines, pyrimidines and amino acids (Blakley, 1969). The enzyme is considered to be the major cellular receptor for several important drugs including met...
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Article history: Received 11 April 2016 Received in revised form 27 June 2016 Accepted 28 June 2016 Available online 1 July 2016 In adulthood, steroid 5-reductases (Srd5) are known to synthesize androgens from testosterone and to play important physiological roles, in particular during reproduction. However, less is known about their regulation and function during early development. To deepen t...
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The percent identity matrices of two sequence multiple alignments between linker histones from chicken and mammalian species are described. Linker histone protein sequences for chicken, mouse, rat and humans, available on public databases were used. This information is related to the research article entitled "Identification of novel post-translational modifications in linker histones from chic...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1997
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.94.8.3554